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Features of Antibiotics Challenges or Mechanisms and Opportunities PDF
A chemocentric view of the molecular structures of antibiotics, their origins, actions, and major categories of resistance Antibiotics Challenges or Mechanisms and Opportunities PDF
Antibiotics: Challenges, Mechanisms, Opportunities focuses on antibiotics as small organic molecules, from both natural and synthetic sources. Understanding the chemical scaffold and functional group structures of the major classes of clinically useful antibiotics is critical to understanding how antibiotics interact selectively with bacterial targets.
This textbook details how classes of antibiotics interact with five known robust bacterial targets: cell wall assembly and maintenance, membrane integrity, protein synthesis, DNA and RNA information transfer, and the folate pathway to deoxythymidylate. It also addresses the universe of bacterial resistance, from the concept of the resistome to the three major mechanisms of resistance: antibiotic destruction, antibiotic active efflux, and alteration of antibiotic targets. Antibiotics also covers the biosynthetic machinery for the major classes of natural product antibiotics.
Authors Christopher Walsh and Timothy Wencewicz provide compelling answers to these questions:
What are antibiotics?
Where do antibiotics come from?
How do antibiotics work?
Why do antibiotics stop working?
How should our limited inventory of effective antibiotics be addressed?
Antibiotics is a textbook for graduate courses in chemical biology, pharmacology, medicinal chemistry, and microbiology and biochemistry courses. It is also a valuable reference for microbiologists, biological and natural product chemists, pharmacologists, and research and development scientists.
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Description of Antibiotics Challenges or Mechanisms and Opportunities PDF
Health, anatomy, physiology, biochemistry, medicine, surgery, and nursing textbooks will likely be at your side throughout your medical studies, and you’ll be reading through countless scientific papers, but you might want to read something beforehand that gives you insight into the world of medicine in practice – whether that’s research, at the clinic or in the operating room. The most featured and reviewed on book Antibiotics Challenges or Mechanisms and Opportunities PDF is available for grabs now here on our website free for students and professionals sole purpose of teaching and education. It has been boasted and proven with thousands of user reviews that it has all the information to make you one of the highly qualified professionals in the world of medicine and its branches. Without a doubt a masterpiece for those who aspire to be doctors or heal those they find in ailment. It is a must read again and again for everyone that can get their hands on this limited edition book. If you are a medical student or are still thinking about it, you will find yourself reading many books like encyclopedia health books. Being a medical student is not easy. Another of the many benefits of reading books is that it reduces stress and anxiety. As a medical student, it is normal for you to feel scared due to being overwhelmed. You’ll be completely focused on the story or advice, which calms you down and makes you happier, especially if you’re reading something happy and moving. When you finish reading, you can be calm enough to look at your problem differently. Every time you read a book, you build some relationship with these characters. Even if you are only different in paper and ink, you are still connected to that character. Sometimes you’re even in their thoughts. This alleviates the feeling of isolation because you feel connected to these characters. It also alleviates feelings of exhaustion and despair when you’re reading something exciting and happy. Download it now.
The Authors
Dimensions and Characteristics of Antibiotics Challenges or Mechanisms and Opportunities PDF
- Identification Number : 1555819303
- Publisher : ASM Press; 2nd edition (February 17, 2016)
- Language : English
- Hardcover : 477 pages
- International Standard Book Number-10 : 9781555819309
- International Standard Book Number-13 : 978-1555819309
- Item Weight : 2.27 pounds
- Dimensions : 7 x 1 x 9.9 inches
- Best Sellers Rank: #1,487,327 in Books
Top reviews
Daniel L. Purich
Quite simply the best…
March 15, 2016
Anyone wishing to learn how antibiotics work and how some bacteria can elude their actions will find much in this book. While many authors are good at “presenting” scientific information, the authors of ANTIBIOTICS: CHALLENGES, MECHANISMS & OPPORTUNITIES excel at “explaining” and “conceptualizing” all you might ever wish to know about one of the great triumphs of the molecular life sciences. After decades at the forefront of this field, this book’s senior author, Professor Chris Walsh, has done it again – masterfully portraying the history, the bioorganic chemistry, the enzyme chemistry, and key cellular events that underpin antibiotic action. Those who have already taken a university-level biochemistry course will be prepared to appreciate this book, but ANTIBIOTICS is more likely to become the standard text for one-semester specialty courses in pharmacology and biological chemistry departments. This reviewer will adopt the book as a go-to reference in a seminar course for gifted third-year undergrads who have already earned early admission to the University of Florida College of Medicine. Learning the intricacies of antibiotics from this impeccable book is likely to foster a commitment to life-long learning.
If there is any flaw at all in this book it is the publisher’s use of low-density paper, which too often reveals text and images on the obverse face of each page. That said, one must commend the authors and publisher for keeping the price in range for most graduate students.
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Francisco Palacios
Good source of information of antibiotics
January 18, 2020
Very good book, arrived in excellent conditions. The information is concise and give the most recent advances in the topic of antibiotics. Surely a very nice survey of info for those who are searching for simple comprehension of antibiotics and the new research at medicinal chemistry.
Andrey Mikhaylov
The one organic chemist needs
June 3, 2020
For me as an organic chemist this textbook is a brilliant.
The approach is much chemical and I love it. It covers all major antibiotic types. Mechanisms are discussed very well.
The last and not the least. I am not a native speaker, so I might be mistaken… But the style, the language is even better. It is Hemingway! It is a real pleasure to read.
An Admirer
A Master Work
February 22, 2016
Great book; amazing illustrations. The reference work on this important topic.
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Top reviews from other countries
dr s j teague
Brings out the chemist in me
Reviewed in the United Kingdom on September 12, 2017
Excellent review by hard core chemists.
Jarrod Johnson
Five Stars
Reviewed in Canada on May 20, 2016
Fantastic book. An awesome keeper.
Five Stars
Reviewed in Canada on November 16, 2016
Reference for University Biology course
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